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Multimorbidity and acute infectious diseases in urban and semi-urban settings in Peru: A mixed-methods study.
Anza-Ramirez, Cecilia; Najarro, Lizzete; Bernabé-Ortiz, Antonio; Diez-Canseco, Francisco; Fottrell, Edward; Abubakar, Ibrahim; Hernández-Vásquez, Akram; Carrillo-Larco, Rodrigo M; Hurst, John R; Miranda, Juan Jaime.
Afiliação
  • Anza-Ramirez C; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Najarro L; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Bernabé-Ortiz A; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Diez-Canseco F; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Fottrell E; UCL Institute for Global Health, University College London, London, UK.
  • Abubakar I; UCL Institute for Global Health, University College London, London, UK.
  • Hernández-Vásquez A; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Carrillo-Larco RM; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Hurst JR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
  • Miranda JJ; UCL Respiratory, University College London, London, UK.
J Multimorb Comorb ; 14: 26335565241256826, 2024.
Article em En | MEDLINE | ID: mdl-38798989
ABSTRACT

Background:

The co-occurrence of chronic diseases and acute infectious events exacerbates disability and diminishes quality of life, yet research in Low- and Middle-Income countries is scarce. We aimed to investigate the relationship between infectious events and multimorbidity in resource-constrained settings.

Methods:

We conducted a sequential mixed-method study in Lima and Tumbes, Peru, with participants having multimorbidity from the CRONICAS Cohort Study. They completed a questionnaire on the occurrence, treatment, and health-seeking behaviour related to acute infectious events. Qualitative interviews explored the perceptions and links between multimorbidity and acute infectious events for a subgroup of participants.

Findings:

Among individuals with multimorbidity, low awareness of chronic conditions and poor medication adherence. The cumulative incidence for respiratory and gastrointestinal infections, the most reported acute conditions, was 2.0 [95%CI 1.8-2.2] and 1.6 [1.2-1.9] events per person per year, respectively. Individuals with cancer (6.4 [1.6-11.2] events per person per year) or gastrointestinal reflux (7.2 [4.4-10.1] events per person per year) reported higher cumulative incidence of infectious events than others, such as those with cardiovascular and metabolic conditions (5.2 [4.6-5.8] events per person per year). Those with three or more chronic conditions had a slightly higher cumulative incidence compared with individuals with two conditions (5.7 [4.4-7.0] vs 5.0 [4.4-5.6] events per person per year). Around 40% of individuals with multimorbidity sought healthcare assistance, while others chose drugstores or didn't seek help. Our qualitative analysis showed diverse perceptions among participants regarding the connections between chronic and acute conditions. Those who recognized a connection emphasized the challenges in managing these interactions.

Interpretation:

Our study advances understanding of multimorbidity challenges in resource-limited settings, highlighting the impact of acute infections on patients' existing multimorbidity burden.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Peru Idioma: En Revista: J Multimorb Comorb Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Peru País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Peru Idioma: En Revista: J Multimorb Comorb Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Peru País de publicação: Reino Unido