Your browser doesn't support javascript.
loading
Community-acquired acute kidney injury in Southeast Brazil and independent risk predictors: a prospective cohort study.
Corrêa, Eric Aragão; Barreto, Joaquim; Lussim, Lygia; Carbonara, Cinthia Esbrile Moraes; Macedo, Etienne; Oliveira, Rodrigo Bueno.
Afiliação
  • Corrêa EA; School of Medical Sciences, Universidade Estadual de Campinas, U.N.I.C.A.M.P., Campinas, SP, Brazil.
  • Barreto J; Laboratory of Atherosclerosis and Vascular Biology, Division of Cardiology, U.N.I.C.A.M.P., Campinas, SP, Brazil.
  • Lussim L; Division of Nephrology, Department of Internal Medicine, School of Medical Sciences, Universidade Estadual de Campinas, U.N.I.C.A.M.P., Campinas, SP, Brazil.
  • Carbonara CEM; Division of Nephrology, Department of Internal Medicine, School of Medical Sciences, Universidade Estadual de Campinas, U.N.I.C.A.M.P., Campinas, SP, Brazil.
  • Macedo E; Division of Nephrology, Department of Medicine, University of California, San Diego, USA.
  • Oliveira RB; Division of Nephrology, Department of Internal Medicine, School of Medical Sciences, Universidade Estadual de Campinas, U.N.I.C.A.M.P., Campinas, SP, Brazil. rbo@unicamp.br.
J Nephrol ; 37(5): 1309-1315, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38809357
ABSTRACT

BACKGROUND:

The prevalence and risk factors for community-acquired acute kidney injury (CA-AKI) are unknown. This study aimed to explore the incidence of CA-AKI in a tertiary care center and to depict the main clinical characteristics related to this condition.

METHODS:

This was a prospective cohort study involving patients admitted to the emergency department (Hospital de Clínicas, UNICAMP, Campinas, Brazil) between January 2019 and September 2021. Adults (≥ 18 yrs) who presented to the emergency room with symptoms potentially associated with an increased risk of AKI were included. Individuals with a prior diagnosis of stage 5 chronic kidney disease or with a confirmed COVID-19 infection were excluded. A score based on clinical signs and symptoms was assigned to predict the risk of severe AKI.

RESULTS:

Of the 261 patients enrolled, CA-AKI was diagnosed in 65 (25%). The CA-AKI group was older [57(± 14) vs. 51(± 18) years, p = 0.02] and had a lower baseline estimated glomerular filtration rate [103 (88-113) vs. 109 (97-121) mL/min/1.73 m2; p = 0.01]. Logistic regression showed that scores ≥ 7 points [odds ratio (OR) 2.8 (1.281-6.133), 95% confidence interval (CI), p = 0.01], age [OR 1.02 (1.007-1.044), 95% CI, p = 0.008] and liver disease [OR 2.6 (1.063-6.379), 95% CI, p = 0.03] were independently related to CA-AKI.

CONCLUSION:

The incidence of CA-AKI was not negligible among patients admitted to a tertiary care center; CA-AKI can be suspected on a clinical basis and confirmed by serum creatinine. Age, liver disease and higher scores in risk prediction tools were related to an increased incidence of CA-AKI.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Injúria Renal Aguda Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Nephrol Assunto da revista: NEFROLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Injúria Renal Aguda Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Nephrol Assunto da revista: NEFROLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália