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Combining Transcranial Direct Current Stimulation With Non-Invasive Interventions for Chronic Primary Pain: A Systematic Review and Meta-Analysis.
Lyra de Brito Aranha, Renata Emanuela; Nascimento, José Diego Sales do; Sampaio, Danielle Dorand Amorim; Torro-Alves, Nelson.
Afiliação
  • Lyra de Brito Aranha RE; Cognitive Neuroscience and Behavior Program, Federal University of Paraíba, João Pessoa, Brazil.
  • Nascimento JDSD; Department of Physical Therapy, Health Science Center, Federal University of Paraíba, João Pessoa, Brazil.
  • Sampaio DDA; Department of Physical Therapy, Health Science Center, Federal University of Paraíba, João Pessoa, Brazil.
  • Torro-Alves N; Cognitive Neuroscience and Behavior Program, Federal University of Paraíba, João Pessoa, Brazil.
Neurorehabil Neural Repair ; 38(8): 616-632, 2024 Aug.
Article em En | MEDLINE | ID: mdl-39075920
ABSTRACT

BACKGROUND:

A growing number of studies has combined transcranial direct current stimulation (tDCS) with other non-invasive non-pharmacological therapies (NINPT) to enhance effects in pain reduction. However, the efficacy of these combined approaches in treating chronic primary pain (CPP) warrants thorough investigation.

OBJECTIVE:

This study aims to evaluate the efficacy of tDCS in conjunction with other NINPT in alleviating pain severity among CPP patients.

METHODS:

We conducted a systematic search for randomized controlled trials (RCTs) comparing the efficacy of tDCS combined with NINPT against control treatments in adult CPP patients. The search spanned multiple databases, including PubMed, EMBASE, LILACS, Scopus, Web of Science, and CENTRAL.

RESULTS:

Our systematic review included 11 RCTs with a total of 449 participants. In our meta-analysis, which comprised 228 participants receiving active-tDCS and 221 receiving sham-tDCS, we found a significant reduction in pain intensity (Standard Mean Difference = -0.73; 95% Confidence Interval (CI) = -1.18 to -0.27; P = .002) with the use of active-tDCS combined with NINPT.

CONCLUSION:

These findings substantiate the therapeutic potential of combining tDCS with other NINPT, highlighting it as an effective treatment modality for reducing pain intensity in CPP patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Crônica / Estimulação Transcraniana por Corrente Contínua Limite: Humans Idioma: En Revista: Neurorehabil Neural Repair Assunto da revista: NEUROLOGIA / REABILITACAO Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Crônica / Estimulação Transcraniana por Corrente Contínua Limite: Humans Idioma: En Revista: Neurorehabil Neural Repair Assunto da revista: NEUROLOGIA / REABILITACAO Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos