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Association between Polypharmacy and Hospitalization among Older Adults Admitted to Emergency Departments for Falls in Guadeloupe: A Retrospective Cohort Study.
Simo-Tabue, Nadine; Letchimy, Laurys; Mounsamy, Ludwig; Rinaldo, Leila; Vainqueur, Larissa; Ntsama-Essomba, Marie-Josiane; Mallet, Guillaume; Boucaud-Maitre, Denis; Tabue Teguo, Maturín.
Afiliação
  • Simo-Tabue N; Unité de Recherche EpiCliV, Université des Antilles, 97233 Fort-de-France, France.
  • Letchimy L; Service de Gériatrie, CHU de Martinique, 97261 Fort-de-France, France.
  • Mounsamy L; Pôle Gériatrie-Gérontologie, Université des Antilles, 97233 Fort-de-France, France.
  • Rinaldo L; CHU de Martinique, 97261 Fort-de-France, France.
  • Vainqueur L; CHU Pointe à Pitre, Université des Antilles, 97233 Fort-de-France, France.
  • Ntsama-Essomba MJ; CHU Pointe à Pitre, Université des Antilles, 97233 Fort-de-France, France.
  • Mallet G; CHU Pointe à Pitre, Université des Antilles, 97233 Fort-de-France, France.
  • Boucaud-Maitre D; Hôpital Central de Yaoundé, Yaoundé P.O. Box 25625, Cameroon.
  • Tabue Teguo M; CHU Pointe à Pitre, Université des Antilles, 97233 Fort-de-France, France.
Healthcare (Basel) ; 12(15)2024 Jul 24.
Article em En | MEDLINE | ID: mdl-39120174
ABSTRACT

Introduction:

Falls are a common geriatric syndrome in older people. Falls are associated with adverse health events such as dependency, unplanned emergency admissions and death. This study aimed to identify the factors associated with fall severity, such as diabetes, hypertension, heart disease, cognitive decline and polypharmacy, as well as sociodemographic characteristics in patients aged 70 years and over admitted to the emergency department in Guadeloupe.

Method:

A single-center, observational, retrospective study of patients aged 70 years and over admitted to the emergency department (ED) of the University Hospital of Guadeloupe for a fall between 1 May 2018 and 30 April 2019 was conducted. Fall severity was defined as the need for hospitalization. Bivariate analysis was used to determine the associations between fall severity and sociodemographic characteristics, comorbidities, history of falls and polypharmacy (defined as the daily use of at least five drugs). Polypharmacy was analyzed as a binary variable (>5 drugs daily; yes or no) in categories (0-3 (ref.), 4-6, 7-9 and ≥10 drugs).

Results:

During the study period, 625 patients who attended the ED for a fall were included. The mean age was 82.6 ± 7.6 years, and 51.2% were women. Of these, 277 patients (44.3%) were admitted to the hospital, and 3 patients (0.5%) died. In the bivariate analysis, only polypharmacy was associated with hospitalization for a fall (OR 1.63 [95% CI 1.33-2.02]). The odds ratios for the polypharmacy categories were 1.46 [95% CI 0.99-2.14], 1.65 [1.09-2.50] and 1.48 [0.76-2.85] for 4-6, 7-9 and ≥10 drugs, respectively.

Conclusions:

Polypharmacy was associated with hospitalization as a proxy for fall severity. A regular review of drug prescriptions is essential to reduce polypharmacy in older adults.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Guadalupe Idioma: En Revista: Healthcare (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: França País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Guadalupe Idioma: En Revista: Healthcare (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: França País de publicação: Suíça