Laboratory diagnosis of yellow fever infections in humans, Alouatta Monkeys and Haemagogus Mosquitoes in Trinidad, 1978-1980
Monography
em En
| MedCarib
| ID: med-16521
Biblioteca responsável:
TT5
Localização: TT5; WC 530 S929 1991
ABSTRACT
The yellow fever epidemic in Trinidad began with an epizootic in Alouatta monkeys in November, 1978. Activity was detected by virus isolation from Alouatta monkeys and from Haemagogus mosquitoes between this date and July 1980. First reports of monkey deaths centered around the Guayaguayare forests of SOuth Trinidad, following which the epizootic spread west to the Moruga area, and north through the Biche Forest Reserve, eventually reaching the north-west Chaguaramas peninsula. Surveillance of febrile persons attending clinics and hospitals was intensified and 18 confirmed cases were identified, from 14 of whom yellow fever virus was isolated. In four cases, diagnoses were made on the basis of liver pathology only. Paired sera were obtained from 10 of 11 persons who survived and in each case serological conversions were obtained by haemaglutination inhibition and more neutralization tests. Yellow fever virus was isolated from 16 of 32 Alouatta monkeys and from 19 of 174 pools of Haemagogus mosquitoes. Two systems were used for virus isolation the Aedes cell line AP-61 and suckling mice. The former proved to be more sensitive, detecting virus in 11.7 percent of 725 specimens inoculated whereas suckling mice detected virus in 7.9 percent of 724 specimens. In 11 instances virus was detected in an animal or mosquito pool by AP-61 but not initially by mouse inoculation whereas the converse was true in only one case (AU)
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Coleções:
01-internacional
Base de dados:
MedCarib
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Tipo de documento:
Congress and conference
/
Monography